Pentobarbital will decrease the level or influence of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Minimal/Significance Not known. pentobarbital will reduce the extent or effect of tamoxifen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. pentobarbital will reduce the level or impact of lumacaftor/ivacaftor by influencing hepatic/intest... https://is-nembutal-a-barbiturate10875.blogsumer.com/30419280/the-fact-about-what-kind-of-drug-is-nembutal-that-no-one-is-suggesting