Environmental or self-antigens and homotypic interactions trigger BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other alerts from your microenvironment and raising the activation of anti-apoptotic and proliferation pathways.31,32 Genomic experiments have determined recurrent mutations in genes regulating tumor mobile-microenvironment interactions,... https://sandram665fxn5.blogchaat.com/profile